Cirrhosis

Scarring of the liver that can stop it working properly. Often silent early on, but serious and requiring specialist management. Community experiences, not medical advice.

Community experiences, not medical advice
Established Evidence

What is cirrhosis?

Cirrhosis is scarring of the liver that can stop it from working properly. The NHS explains that healthy liver tissue is replaced by scar tissue, which prevents the liver from working normally. NICE NG50 provides detailed guidance on assessment and management in adults over 16.

Many people with cirrhosis do not have symptoms, especially early on. This means it is often diagnosed when tests are done for other reasons, or when complications develop. It can be life-threatening and needs specialist management.

Common causes

  • Alcohol misuse — long-term heavy drinking is a leading cause
  • Hepatitis B or C — viral infections that damage the liver over time
  • NAFLD — non-alcoholic fatty liver disease can progress to cirrhosis in some people
  • Autoimmune liver disease — for example, primary biliary cholangitis
  • Genetic conditions — for example, haemochromatosis or Wilson's disease

Cirrhosis is distinct from NAFLD. NAFLD can progress to cirrhosis, but most people with NAFLD do not develop it. This page covers cirrhosis itself; fatty-liver management detail stays on the NAFLD guide.

Symptoms

Early cirrhosis may cause no symptoms. As it progresses, symptoms can include:

  • Tiredness and weakness
  • Loss of appetite and weight loss
  • Nausea
  • Tenderness or pain around the liver area
  • Itchy skin
  • Jaundice (yellowing of the skin and eyes)
  • Swelling in the legs, ankles, or abdomen (ascites)
  • Vomiting blood or passing blood in stools
  • Confusion or memory problems (hepatic encephalopathy)

Complications

Clinicians and NICE NG50 often describe cirrhosis as compensated (the liver is still working well enough that major complications have not appeared) or decompensated (complications such as ascites, variceal bleeding, or encephalopathy have developed). NICE NG50 sets out recommendations for assessing and managing the main complications:

  • Ascites — fluid in the abdomen
  • Variceal bleeding — bleeding from enlarged veins in the oesophagus or stomach
  • Hepatic encephalopathy — confusion caused by the liver not clearing toxins
  • Liver cancer — people with cirrhosis have a higher risk

These complications need urgent medical attention and specialist hospital care. Prescribing advice (for example beta-blocker dosing for varices) belongs with clinicians and NICE NG50.

Approaches people discuss

Cirrhosis management is highly medicalised and hospital-centric. The NHS and NICE NG50 guide clinical care. Community discussion tends to focus on lifestyle, adherence, nutrition, and knowing when to seek urgent help.

  • Established Stopping alcohol completely if alcohol is a cause. The NHS states that stopping drinking can sometimes stop cirrhosis getting worse. Sources: NHS cirrhosis; NICE NG50.
  • Established Medication adherence — taking prescribed medicines for hepatitis, autoimmune disease, or complications as directed by specialists. Sources: NICE NG50.
  • Established Nutrition — maintaining adequate calorie and protein intake; malnutrition is common in cirrhosis and dietitian input is often needed. Sources: NICE NG50.
  • Established Monitoring for complications — knowing the warning signs (confusion, vomiting blood, sudden abdominal swelling) and seeking urgent care. Sources: NHS; NICE NG50.

What not to self-manage

These are cautions, not approaches people discuss:

  • Do not use “liver detox” products, extreme cleansing diets, or unproven liver supplements — these are not established treatments for cirrhosis, and some can be harmful when the liver is already scarred. The NHS advises checking with a pharmacist or doctor before taking any medicines, including herbal medicines, if you have cirrhosis.
  • Do not treat cirrhosis as a self-managed NAFLD lifestyle plan — once cirrhosis is present, care is specialist and hospital/clinic-centric; lifestyle changes support care but do not replace it.
  • Do not adjust or start medicines for varices, ascites, or encephalopathy from forum advice — dosing and choice belong with the clinical team and NICE NG50.

Medical Research

NICE NG50 — Cirrhosis in over 16s: assessment and management

NICE guideline NG50 covers assessment and management of cirrhosis and its complications (ascites, variceal bleeding, hepatic encephalopathy) in adults. Updated September 2023.

NICE Guideline
View NICE NG50

NICE NG50 — Information for the public

Plain-language summary of NG50 for people with cirrhosis and their carers, covering what care to expect and key complications.

NICE Information for the public
View NG50 public info

NHS — Cirrhosis overview

The NHS provides patient-facing information on cirrhosis, including causes, symptoms, diagnosis, treatment, and living with the condition.

NHS Patient information
View NHS guidance

Medical Disclaimer

The information provided is for educational purposes only and is not intended as a diagnosis, treatment, or substitute for professional medical advice. Always consult with a qualified healthcare provider about your specific situation. Cirrhosis requires specialist management; seek urgent care for vomiting blood, black stools, sudden confusion, or rapidly worsening abdominal swelling.